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New Guidelines on Testing Kids DNA-the Cliff s Notes Version

Exomes are big news. Sequencing of the protein-encoding part of the genome is increasingly solving medical mysteries in children. It began with Nicholas Volker and his recovery from a devastating gastrointestinal disease with a stem cell transplant once his exome sequence revealed his problem.And my recent Medscape assignments reveal the trend: 7 of 12 kids’ exomes leading to diagnosis at Duke University (from May 10, 2012); whole genomes of 5 infants from the neonatal intensive care unit at Children’s Mercy Hospital and Clinics in Kansas City, Missouri (from October 3), in just 50 hours each, focusing on 600 single-gene diseases; and 300 patients at the Whole Genome Laboratory at the Baylor College of Medicine, with 300 more waiting -- 85% of them kids (from November 9, 2012).But wait.

February 21, 2013 — Ricki Lewis

#SciAmBlogs Wednesday - Stamp Biodiversity, Electric Vehicles, Vintage Space, Obesity Coverage, Meteors, and more.

As usual on Wednesdays, we have the new Video of the Week. - Laura Jane Martin - Postage Stamps Overlook Earth's Tiny Creatures  - Bora Zivkovic - Introducing: Kate Prengaman  - Tali Trigg - Electric Vehicle Deployment – Where Should We Be Today?  - Carin Bondar - Vintage Space: Historical Spaceflight on Film  - Dana Hunter - Parícutin: “Here Is Something New and Strange”  - Kalliopi Monoyios - The Coolest Photo My iPhone Never Took  - DNLee - Obesity Coverage in Black Newspapers Mostly Negative, University of Missouri Study Finds  - Scicurious - On writing it down  - John Matson - Could Another Chelyabinsk-Scale Meteor Sneak Up on Us? =======================Conversations on our articles and blog posts often continue on our Facebook page - "Like" it and join in the discussion.

STAFFFebruary 20, 2013 — Bora Zivkovic

The Coolest Photo My iPhone Never Took

Alex Wild over at Compound Eye is quick to point out with his Thrifty Thursday posts that great photos can be taken with relatively inexpensive equipment...

February 20, 2013 — Kalliopi Monoyios

Map of Brain's Speech Centers May Help `Locked-In' Patients Talk

Electrode placement on speech motor cortex Wilder Penfield's famous homonculus map of the brain had a large area on one side capped by a gaping cartoon mouth labeled simply "vocalization."During the 1930s, Penfield stimulated that same area, but was unable to elicit any recognizable utterances.

STAFFFebruary 20, 2013 — Gary Stix

Could Another Chelyabinsk-Scale Meteor Sneak Up on Us?

Credit: ESA When a 17-meter asteroid barreled into Earth’s atmosphere over central Russia on February 15, releasing a powerful shock wave that injured more than 1,000 people, many observers wondered how such a momentous event could arrive unheralded.

February 20, 2013 — John Matson

It Happened In Space!

Video of the Week #80, February 20th, 2013: From: Vintage Space: Historical Spaceflight on Film by Carin Bondar at PsiVid . Source: Amy Shira Teitel on YouTube Space Lab - Scientific American Historian Amy Shira Teitel has a lot to say about spaceflight.

February 20, 2013 — Bora Zivkovic

On writing it down

Sci is at Neurotic Physiology today with a plea. A plea to new grad students, to new postdocs, to new undergrads. A plea to WRITE IT DOWN. All of it.

February 20, 2013 — Scicurious

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Limited Time Offer: Scientific American Health & Medicine Premiere Issue

Limited Time Offer: Scientific American Health & Medicine Premiere Issue