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Guest Blog

Hallmarks of Cancer 6: Tissue Invasion and Metastasis

The Hallmarks of Cancer are 10 underlying principles shared by all cancers. You can read the first five Hallmarks of Cancer articles here. The Sixth Hallmark of Cancer is defined as “Tissue Invasion and Metastasis.” A growing tumor will eventually spawn pioneer cells; these move out of the original clump of mutant cells to invade [...]

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MIND Guest Blog

Can Video Games Diagnose Cognitive Deficits?

Five brain-training games available as an iPad “app” from Lumosity were evaluated as tests of cognitive dysfunction in cirrhosis: (a) Circles is a test of spatial orientation, information processing speed and attention. Colored circles appear one at a time and a user must decide whether each is a match when compared with the circle that showed up earlier. (b) Color Match evaluates selective attention, cognitive flexibility and processing speed. The names of two colors appear and the test-taker must decide whether or not the top word names the font color of the bottom word. (c) Memory Matrix taps visuospatial memory. A pattern of tiles appears on a grid; when the pattern disappears, a test-taker attempts to recreate it. (d) Lost in Migration examines attention as well as visual field and focus. Five birds appear and a user indicates the direction of flight of the center bird. (e) Chalkboard Challenge involves quantitative reasoning. A player must determine which arithmetic figure has the greatest value between two choices.

This blog is the third in a series of guest posts on technology and the brain to celebrate Scientific American Mind’s 10-year anniversary. The magazine’s special November/December issue similarly highlights the interface between code and thought in profiling a future, more digital YOU. Video games are an increasingly common pastime, especially for children, adolescents and [...]

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The Quest: $84,000 Miracle Cure Costs Less Than $150 to Make

What are the likely manufacturing costs for sofosbuvir (Brand name: Sovaldi), the newly approved miracle drug that cures hepatitis C at a cost of $84,000 for the full 12-week course of treatment? Anywhere from $68 to $136 for the full course, according to an analysis that was published in Clinical Infectious Disease (CID) in January—which was [...]

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