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Posts Tagged "dementia"

Observations

Patients Clamor for Cancer Drug That Shows Promise for Alzheimer’s in Mice

The pharmaceutical industry has beat a concerted retreat from developing drugs for diseases that affect the brain, stymied by the lengthy development times for these agents and a string of failures. Despite the evident risks,  a new study shows how industry leaders should perhaps be taking the long view. The report online last week in [...]

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Observations

Alzheimer’s Risk Linked to Common Complaints, from Poor Eyesight to Denture Trouble

As we age, all sorts of things may start to break down. Joints ache, or vision fails, and or maybe cognitive abilities falter. The leading known risk for getting Alzheimer’s disease or other forms of dementia is simply getting older, followed, some studies suggest, by major illnesses, such as diabetes, heart disease, high blood pressure [...]

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Observations

Being overweight in midlife might increase chance of dementia later

overweight middle age dementia risk

Obesity and dementia have a well-established connection in the medical literature. But a new study shows that just being overweight—with a BMI of 25 or above—in middle age might also significantly increase the odds that a person develops dementia later in life. In a study of 8,534 both identical and fraternal twins aged 65 and [...]

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Observations

Aerobic exercise bulks up hippocampus, improving memory in older adults

older adults walking increase size of hippocampus, improve memory

Many studies have linked exercise with improved brain health later in life. Now a new controlled trial reveals more about how aerobic activity might be helping to bolster the brain by beefing up the hippocampus. As we age, parts of the brain tend to shrink—even in the absence of neurocognitive diseases, such as dementia or [...]

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Observations

Could a dose of arthritis medication prevent postsurgical memory loss?

surgery can lead to cognitive decline from inflammation

Like people, mice sometimes show signs of general confusion and memory loss after surgery. Common major (noncardiac) procedures, such as orthopedic operations, can lead to postsurgical cognitive decline in some seven to 26 percent of patients. And though it’s usually temporary, this mental fogginess has been linked to worse overall recovery and long-term cognitive problems. [...]

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Observations

Extra weight around the hips associated with greater cognitive decline in older women

overweight woman who may be at higher risk for dementia

The spare tire many U.S. adults carry around their middles has been linked to a host of health risks, including, some research has found, decreased cognitive ability in men. The relationship between weight and dementia has been controversial, however, and some researchers have had difficulty finding a consistent association between these two health issues—especially in [...]

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Observations

One in 10 veterans returns from combat in Iraq reporting serious mental health issues

iraq war veterans 10 ptsd depression functional

Veterans of war have been known to suffer from high incidence of post-traumatic stress disorder (PTSD), depression and traumatic brain injury in addition to any physical wounds. And a new study of thousands of U.S. Army soldiers returning from combat duty in Iraq found up to 31 percent reported symptoms of PTSD or depression as [...]

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Observations

Untreated vision problems linked to dementia in the elderly

Elderly people with untreated poor vision are significantly more likely to suffer from Alzheimer’s disease and other forms of dementia than their clear-sighted counterparts, according to a study published online February 18 by the American Journal of Epidemiology. What’s more, the study suggests that vision problems may be a contributing factor in the development of [...]

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Observations

Could a genetic cholesterol control protect some people from dementia?

dementia, alzheimer

The more information about cholesterol’s complex health role that comes to light, the more curious are the ways it seems to be important. A growing body of research has noted the substance’s importance in the brain (which holds about a quarter of the body’s total cholesterol). Now, a new study adds another layer of understanding [...]

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Observations

Should advanced dementia be considered a terminal illness?

dementia terminal illness

Advanced dementia has often been treated as an amalgamation of symptoms in the aging, rather than a deadly illness in itself. A new study, published online today in The New England Journal of Medicine, proposes that it may be beneficial—for patients and caretakers alike—to take the latter approach. "As the end of life approaches, the [...]

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Talking back

Gold Standard Trial Affirms Role of Diet, Exercise and Such to Prevent Dementia

In 2010, the National Institutes of Health held a conference to determine what measures, including behavioral steps like exercise and diet, could be taken to reduce the risk of Alzheimer’s. A report prepared specifically for that conference by the Agency for Healthcare Research and Quality (AHRQ) made an assessment of  the existing evidence for preventive [...]

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Talking back

Early Trial of Doctor’s Office Test to Predict Dementia Before First Symptoms

Until very recently, the only way to provide a firm diagnosis of Alzheimer’s was through a brain autopsy. Things are starting to change. Brain imaging and spinal taps have now started to look for the plaques and tangles that are the hallmarks of the neurodegenerative disease in living patients. These techniques are now being tested [...]

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