Clinical Trials for Beginners: Ethics – Pediatric Anthrax Vaccine Case Study

Having looked at the rampant conflicts of interest surrounding the anthrax vaccine and a bit at the logistics of the proposed pediatric vaccine trial let’s look at the trial in the context of ethical principles. Ethical context The need for ethical guidelines came to vivid attention during World War II, when the Nazis tortured many [...]
Keep reading »Anthrax vaccine – To the victor, the spoils

In my last post, we began to play “Follow the Money” to better understand the history of the anthrax vaccine and the current proposal to test the vaccine on children. Conflicts of Interest-Case Study Major issues with the anthrax vaccine include safety, conflicts of interest and the lobbying power of the drug developer. I don’t [...]
Keep reading »Anthrax, anthrax, everywhere…
May 22nd, 2012 |
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This past week brought news about another successful bioterrorism response drill, effectively delivering hypothetical medicines to protect the citizens of Baltimore from a hypothetical anthrax attack. Frankly, I always shake my head in dismay when I read of such preparedness exercises. I think back to my childhood, with its “duck and cover” Cuban missile crisis [...]
Keep reading »Anthrax Toxicity Depends on Human Genetics
February 6th, 2012 |
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The white powder that arrived in envelopes addressed to lawmakers and journalists in 2001 proved to be a deadly delivery for several people. The lethal substance—spores commonly known as Anthrax (from the bacterium Bactillus anthracis)—can cause a toxic reaction in a host’s blood stream, killing cells and leading to tissue damage, bleeding and death. But [...]
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