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Lab Rat

Lab Rat

Exploring the life and times of bacteria

A farewell to Lab Rat

When I first started a science blog, back in the summer of 2008, I wasn’t quite sure what to expect from it. It was started mostly for me, to encourage me to read more papers and write about science.

December 15, 2014 — S.E. Gould
Shooting the messenger: small RNA as a target for antibiotics

Shooting the messenger: small RNA as a target for antibiotics

All living cells contain DNA; the code for producing every protein needed by the cell. As DNA is important it needs to be kept safe. Plants and animals keep their DNA tightly twisted and organised inside a double-membrane bound nucleus while bacteria keep their DNA coiled up in a big circle, with the occasional loop [...]

October 12, 2014 — S.E. Gould

Lab Rat Lecture

Last month I had the privilege of being invited as a speaker for the Blogging Microbes event at the University of Nottingham. Hosted by Ivan Lafayette it was a great discussion of the role of blogs, twitter, and podcasts in communicating science, particularly microbiology, to a wider audience.

October 5, 2014 — S.E. Gould
Glowing fungi for studying infectious diseases

Glowing fungi for studying infectious diseases

When studying how infections grow and spread it is always helpful to be able to see the organism causing the disease. There are currently a range of microbial and labelling techniques available to view micro-organisms within the cells they infect, and one of the most useful is bioluminescence imaging.

August 3, 2014 — S.E. Gould

Salmonella Prefers One Gut Nutrient Once Pathogenic

As antibiotic resistance increases the search for new anti-bacterial treatments becomes more and more important. One way to design anti-bacterials is to find specific biochemical pathways that the bacteria require to survive, and develop drugs that block off these pathways.

July 13, 2014 — S.E. Gould

Arctic creepy-crawlies part II: woolly bear caterpillars

This is the second part of my two-part mini series on Arctic creepy-crawlies. Part I: ice worms can be found here. Part II: Woolly bear caterpillar The Arctic woolly bear moth (Gynaephora groenlandica) is found in Greenland and Canada around the Arctic Circle.

June 29, 2014 — S.E. Gould

Arctic creepy-crawlies part I: the ice worms

Following my previous post on wildlife diseases, I’ve been in a fairly multicellular mood. Rather than try and turn my mind back to bacteria I decided to get it out of my system by finishing the month with a two part mini-series on creepy-crawlies that survive in some of the harshest conditions on earth; the [...]

June 28, 2014 — S.E. Gould

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